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Public Affairs Discussion Group
"STEM
CELL RESEARCH: Science, Ethics, and Prospects"
April 6, 2007
Crawford Hall, Room 9 & 11 - The Inamori Center
12:30 p.m. to 1:30 p.m.
(Lunch and refreshments will be provided)
Sponsored by: Case Western Reserve University Center for Policy Studies and
The National Center for Regenerative Medicine
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Gregory L. Eastwood M.D. - Interim
President at Case
Western Reserve University
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Insoo
Hyun , Ph. D. - Assistant Professor of Bioethics at
Case Western Reserve University |
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Horst
von Recum, Ph.D. - Assistant Professor Biomedical
Engineering at
Case Western Reserve University |
The use of both adult and embryonic
stem cells for medical treatment has been a subject
of great political controversy. There are ethical
and political issues about both research and
treatment. Yet the stakes may be overstated by both
sides, in a competition between political and
scientific exaggeration.
What is the state of the science? What is its
potential? How do policies affect the science? What
are the ethical issues about research? If the
research is successful, would that raise new ethical
issues about treatment? Professor von Recum will
speak about the science; Professor Hyun about the
ethics; and then President Eastwood will offer his
perspectives as both a physician and a medical
school and university leader.
This is a special event of the Friday Public Affairs
Lunch sponsored by the Case Western Reserve
University Center for Policy Studies.
More About Our
Guests
Dr. Eastwood is the interim president of
Case Western Reserve University, having taken the
helm June 2, 2006, following the resignation this
past spring of Edward M. Hundert, M.D.
Before accepting the interim post, the Case alumnus
and former board of trustees member, served as president
of SUNY Upstate
Medical University in Syracuse, NY, since January
1993. Upstate Medical University is comprised of the
University Hospital, four professional colleges
(medicine, nursing, health professions, and graduate
studies), and a clinical campus in Binghamton, NY. With
an annual budget of nearly $800 million and a workforce
of over 6,300 people, Upstate is Central New York's
largest employer.
Dr. Eastwood received his B.A. in 1962 from
Albion College (Phi
Beta Kappa) and his M.D. in 1966 from Case Western
Reserve University School of Medicine (Alpha Omega
Alpha). He completed a residency in internal medicine at
the Hospital of
the University of Pennsylvania and a fellowship in
gastroenterology at the
Boston University Medical Center sponsored by the
National Institutes of Health.
He then served two years on the Clinical
Investigation Service at the Philadelphia Naval
Hospital. Subsequently, he held faculty appointments at
Harvard
Medical School and the
University of
Massachusetts Medical School, where he was director
of the gastroenterology section and associate dean for
admissions. Before coming to Syracuse, Dr. Eastwood was
dean of the Medical
College of Georgia in Augusta.
Over the past 15 years, Dr. Eastwood's professional
interests have included the responsibilities of academic
health centers to the health of the community, the role
of leadership in academic health centers, bioethics, and
ethics of academic health organizations. His research
interests have been in gastrointestinal epithelial
renewal, neoplastic disorders, mechanisms of mucosal
injury and protection, and peptic ulcer disease. He has
authored 125 articles and book chapters and has written
or edited several books.
Dr. Eastwood is married to Lynn Marshall Eastwood
(CIT '66). They have three daughters, Kristen A.
Eastwood Bowers, Lauren E. Eastwood, Ph.D., Kara L.
Eastwood Grace, M.D., and four grandchildren, Caitlin
Eastwood Bowers, Nicholas Eastwood Bowers, Hunter
William Grace, and Adelaide Lee Grace.
Insoo Hyun received his BA and MA in
philosophy from Stanford University, and his Ph.D.
in philosophy from Brown University. Most of his
early training in philosophy focused on ethical
theory and epistemology; under the direction of his
dissertation supervisor, Dan Brock, he later came to
develop a predominant interest in biomedical ethics.
Dr. Hyun's scholarly interests include human
embryonic stem cell research ethics, cross-cultural
issues in informed consent, multiculturalism and patient
autonomy, and health resource allocation. His bioethics
publications have appeared in Nature, The
Hastings Center Report, The Journal of
Clinical Ethics, The Kennedy Institute
of Ethics Journal, and The Cambridge
Quarterly of Healthcare Ethics, among others.
In 2005, Dr. Hyun was awarded a Fulbright Research
Award by the U.S. Department of State to spend the
summer studying the ethical, legal, and cultural
dimensions of human research cloning in South Korea.
His work focused on improving the informed consent
procedures for oocyte and somatic cell donation for stem
cell research to be used by researchers at the World
Stem Cell Hub in Seoul.
Dr. Hyun has been actively involved with the
International Society for Stem Cell Research (ISSCR),
the leading professional organization for stem cell
scientists around the world. In 2006, Dr. Hyun served
as Chair of the Subcommittee on Human Materials
Procurement for the ISSCR's International Guidelines
Task Force headed by George Daley. Dr. Hyun is also the
current Chairperson of the ISSCR's Ethics and Public
Policy Committee.
The research in Horst von Recum's
lab is on tissue engineering blood vessels either for
use as small diameter implants, or for pre-vascularizing
polymer scaffolds for other tissue engineering
applications. To this end he examines the
differentiation of stem cells, both embryonic and
hematopoietic to become the various components of blood
vessels. Stem cells show great promise as tissue
engineering tools both in their unlimited replication
potential and plasticity. Recent progress has shown that
stem cells can be differentiated into circulating
endothelial precursors, and it is these cells which
cause repair and regeneration of large vascular defects.
Horst von Recum is are also
investigating the use of novel stimuli-responsive
polymers for use in cell, gene, and drug delivery. These
polymers can allow binding and loading under one
condition, and release or expression under another
condition. We are examining the use of these polymers as
scaffolds for engineered tissues, as coatings for
existing biomaterial implants, and as selection
substrates in the identification of novel angiogenic
factors through systems biology approaches.
Spring Semester
Schedule
Beginning on February 2, the Friday Lunch will
move back to Crawford Hall, in ROOM 9. Room 9 is within
the Inamori Center, on the basement level of Crawford.
It is very kind of Bill Deal, Director of the Inamori
Center, to make this room available on a regular basis.
Thank you, Bill!
Room 9 seats 35, with a central table and also chairs
along the wall. It should be a better setup than
Guilford. If we expect a large crowd, we may be able to
open a partition and join up with Room 11.
There will, however, be a class in the room until 12:20.
Therefore it will not be possible to get there much
before the lunch begins. On the other hand, people who
are a bit early should be able to hang out in the
Tomlinson food court. I believe the underground passage
from Tomlinson to Crawford will be restored when
construction is finished.
Coffee will be provided from the SAGES Cafe'. Which
should mean very good coffee.
The tentative schedule of speakers, so far:
January 26: Phil (Perkins Professor of
Physics-Case Western Reserve University) and Sarah
Taylor, Wind Power and All of It's Aspects -
Environmental, Energy, Economic, Aesthetic, and
Maybe More.
February 2: Ken Grundy, Marcus Hanna Professor
Emeritus of Political Science, on subject to be
determined
February 9: Paul Schroeder, Visiting Lecturer in
Political Science and from Families of the Fallen for
Change, on what to do in Iraq
February 16: Mark Turner, Professor of Cognitive
Science, on cognition and politics
February 23: Mel Goldstein, Professor of
Anthropology, on why the Chinese are winning in Tibet
March 2: Susan Helper, Professor of Economics, on
strategies for American workers within the current
global competition.
March 9: Baiju Shah, President, Bioenterprise
Corporation, on the new economic prospects in Cleveland.
March 16: Break
March 23: Mike Aronoff of Cuyahoga County on the
evaluation of sexual predators for the courts―are they
really dangerous, and can we predict if they will reoffend?
March 30: Lewis R. Katz,
John C. Hutchins Professor; Director of the Master
of Laws in U.S. and Global Legal Studies program at Case
Western Reserve University,
on the Ups and Downs of Running for
Congress.
April 6:
Horst von Recum, Assistant Professor of Biomedical
Engineering; Insoo Hyun, Assistant Professor of
Bioethics; and Greg Eastwood, Interim President of Case
Western Reserve University on Stem Cell Research.
April 13: Marixa Lasso, Assistant Professor of
History: Drugs, War, and Coffee in Colombia
April 20: Mark Joseph, Assistant Professor,
Mandel School of Applied Social Sciences: Mixed-Income
Development as an Approach to Addressing Urban Poverty
April 27: Christine Cano, Associate Professor of
French, on the French elections (this date falls between
the first round and the runoff election)
Parking: Normally 6 parking spaces are reserved in
the CWRU visitors lot off of Euclid Avenue for the
Friday Public Affairs Discussion Group lunches.
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